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DEMO-001
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Clinical Scenario
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A 62-year-old male of Afro-Caribbean heritage with a history of hypertension and osteoarthritis attends the community pharmacy for a blood pressure review. His clinic BP is 154/94 mmHg, confirmed with repeat daytime ABPM of 146/90 mmHg. He has no prior history of diabetes or renal impairment. Baseline U&Es are normal (eGFR > 90 mL/min/1.73m², K+ 4.4 mmol/L).

According to NICE NG136 hypertension guidelines, which of the following is the most appropriate initial pharmacological therapy?

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